- more >>
- Nucleic Acids Research Publication
- Nucleic Acids Research- June 22, 2010 - A novel template design for single-molecule sequencing is introduced, a structure we refer to as a SMRTbellTM template. more >>
- Gen-Probe Invests $50M in PacBio; Companies in Co-Development Collaboration
- Press Release- June 17, 2010 - Gen-Probe Incorporated (NASDAQ: GPRO) and Pacific Biosciences announced today that Gen-Probe has made a $50 million strategic investment in Pacific Biosciences, a private sequencing company. more >>
- Expression Analysis® to Adopt Pacific Biosciences Platform
- Expression Analysis- May 24, 2010 - Expression Analysis, a leading provider of genomic services for clinical trials and research, announced today that it has agreed to purchase a PacBio RS DNA sequencing system more >>
- Nature Methods publication
- Nature Methods- May 9, 2010 - Turner and colleagues use this approach to identify methylated nucleotides in E. coli and in synthetic templates. more >>
- Science Paper - New Hot Paper Based on Citation Rate
- Science Watch- May 2010 - Jonas Korlach & Steve Turner talk with ScienceWatch.com and answer a few questions about this month's New Hot Papers in the field of Multidisciplinary. more >>
- Pacific Biosciences Team Demonstrates Method for Directly Detecting Methylation During SMRT Sequencing
- Genome Web- May 10, 2010 - Researchers from Pacific Biosciences reported today that they have developed a single-molecule, real-time sequencing-based method for directly detecting DNA methylation patterns without bisulfite or other treatments more >>
- TiE Announces TiE50 Winners
- TiE- May 10, 2010 - TiE, the organizer of TiEcon 2010, the world's largest conference for entrepreneurs, announced the winners of the TiE50 Awards. Selected from among nearly four thousand nominees, and after almost 100 thousand votes more >>
- Seeing more sequences: Driving DNA discovery
- BioOptics World- May 1, 2010 - To further focus on DNA for sequencing, Pacific Biosciences (Menlo Park, CA), uses zero mode waveguides (ZMWs) that direct the illumination and detection. more >>
- SMRT Analysis of Ribosome Synthesis Published in Nature
- Nature- April 14, 2010 - Single-molecule studies allow us, for the first time, to follow the synthesis of full-length proteins in real time. READ PAPER more >>
- Working For a Biotech Start-Up
- Chemical & Engineering News- April 12, 2010 - Fledgling firms offer rewards that sometimes outweigh the risks of conducting high-stakes research on a fast track more >>
- Companies riding the genome wave
- Reuters- April 5, 2010 - Illumina and Life Technologies are sitting at the top of the market for genome sequencing, but next-generation companies with big ideas to cut the cost of sequencing are nipping at their heels. more >>
- The $1000 Genome: Coming Soon?
- Drug Discovery & Development- April 1, 2010 - DNA sequencing has evolved through two generations and is now on its third, with technology providers racing to sequence a complete genome for $1000 or less. more >>
- Multiple personal genomes await
- Nature- April 1, 2010 - Genomic data will soon become a commodity; the next challenge — linking human genetic variation with physiology and disease — will be as great as the one genomicists faced a decade ago, says J. Craig Venter. more >>
- Award recognizes PacBio founder's achievements
- Kauffman Foundation- March 12, 2010 - Steve Turner Awarded 2010 Ewing Marion Kauffman Foundation Outstanding Postdoctoral Entrepreneur more >>
- PacBio ranked #1 Venture-backed company in US
- The Wall Street Journal- March 9, 2010 - Pacific Biosciences was named #1 in a Top 50 list by VentureSource/Wall Street Journal of the most promising venture-backed companies in the U.S. more >>
- Video: Pacific Biosciences Speeds DNA Sequencing
- The Wall Street Journal.com- March 8, 2010 - Pacific Biosciences is working on a DNA sequencing process that it says will allow a person's genome to be sequenced in under an hour for less than $100 more >>
- Toward personalized medicine: 3G DNA sequencing
- OptoIQ- March 1, 2010 - Just on the horizon, new DNA sequencing systems promise real-time processing at reduced cost with single-molecule resolution more >>
- PacBio Developing Chip Technology for Highly Multiplexed 'V2' Sequencers
- In Sequence- February 23, 2010 - As it prepares to roll out its first single-molecule real-time sequencing instrument to early-access customers this summer, Pacific Biosciences is already working on a new highly multiplexed version of its technology more >>
- PacBio Names First 10 Customers
- In Sequence- February 23, 2010 - Pacific Biosciences this week disclosed the first 10 early-access customers for its single-molecule real-time sequencer, which include genome centers and other academic institutions in North America more >>
- Pacific Biosciences Named One of Technology Review's 50 Most Innovative Companies
- Technology Review- February 23, 2010 - To select the 50 most innovative companies in the world, the editors of Technology Review looked for those that over the last year have demonstrated their superiority at inventing technology more >>
- Pacific Biosciences Names First Ten Early Access Customers
- Bio-IT- February 23, 2010 - Pacific Biosciences has announced its first ten early access customers for its next-generation DNA sequencing system- a real-time detection method at the single-molecule level. more >>
- Speedy Prototype Gene Decoders Sold
- Forbes- February 23, 2010 - Ten prototypes of a new, very fast DNA sequencing machine have been sold to customers including Baylor College of Medicine, Stanford University and the crop giant Monsanto, for $695,000 each. more >>
- PacBio Teams with Sample Prep, Informatics Firms
- In Sequence- February 16, 2010 - In preparation for the commercial launch of its single-molecule real-time DNA sequencing system in the second half of this year, Pacific Biosciences has teamed up with almost a dozen companies who will develop more >>
- PacBio's Eleven: Pacific Biosciences Announces Founding Technology Partners
- Bio-IT World- February 16, 2010 - PacBio, the next-generation sequencing company that intents to release the first version of its single molecule DNA sequencing instrument later this year, has announced a partner program featuring eleven leading more >>
- In Advance of Sequencer Launch, PacBio Primes the Informatics Pump via Partner Program
- BioInform - February 16, 2010 - Pacific Biosciences, slated to launch a single-molecule sequencer in the second half of this year, has targeted bioinformatics as a key focus for a new program intended to help smooth any speed bumps that its customers may more >>
- Genomic Advances of the 2000s Demand an Informatics Revolution
- Xconomy - January 14, 2010 - We have witnessed some of the most striking technological and scientific innovations in humankind during the first decade of the new millennium. more >>
- DNA Sequencing Forges Ahead
- Chemical & Engineering News - December 14, 2009 - Advances in DNA sequencing technology are making applications of whole-genome sequencing a reality. more >>
- Speed Freaks
- Journal of Life Sciences - Fall 2009 - The race is on to sequence whole genomes for $1,000, but already companies are talking about shattering that mark and making scans no more expense than routine procedures such as blood and urine tests. more >>
- Tech's Future Stars: The World Economic Forum picks promising pioneers
- Forbes.com - December 3, 2009 - Want to know which company will be the next Google? It could be Metabolix, a company from Cambridge, Mass., that grows biodegradable plastic in plant. Or British company Playfish, which creates addictive videogames more >>
- PacBio Reveals Commercial Specs; Initial Focus on Long Reads, Short Runs, Low Experiment Cost
- In Sequence - November 17, 2009 - Pacific Biosciences this week revealed a number of performance specifications for its first commercial single-molecule real-time DNA sequencer, due to be released during the second half of 2010, as well as a roadmap for more >>
- World Economic Forum honors Bay Area techies
- SF Gate - December 4, 2009 - The Bay Area flexed its innovation muscles Thursday, with local companies winning 12 of the 26 Technology Pioneers Awards handed out by the World Economic Forum. more >>
- WEF Announces 2010 Tech Pioneers: The coveted annual awards program highlights entrepreneurs whose innovations have the potential to change the world
- Business Week - December 3, 2009 - Innovation in the trillion-dollar-per-year construction industry has been pretty sluggish over the past century. The low-tech method for producing standard gypsum drywall, for instance, was invented in 1917. more >>
- Silicon Valley tech pioneers honored by World Economic Forum
- San Jose Business Journal - December 3, 2009 - Nine Silicon Valley companies were honored as technology pioneers by the World Economic Forum, an international nonprofit focused on entrepreneurship in the global public interest. more >>
- The Life Sciences Revolution - Semiconductor Manufacturing Technology is Enabling the Life Sciences Sector to Develop
- Semiconductor developments during the last five decades or so have transformed the electronics industry beyond recognition. Now, the amazing techniques developed by semiconductor manufacturers are doing something similar for an entirely different more >>
- The OnDC 100 - Top Private Companies of 2009
- AlwaysOn - October 8, 2009 - AlwaysOn is pleased to present the first annual OnDC Top 100 List, our pick for the top 100 private companies contributing to the renewed and continued prosperity of our country. more >>
- How Big Could Pacific Biosciences Get?
- peHUB - October 8, 2009 - The gene sequencing company is one of the top venture fundraisers of the year so far, with a $68 million round in August that took its venture haul to $266 million. more >>
- NHGRI Uses Recovery Act Funds to Accelerate Genome Research to Improve Human Health
- NHGRI - October 8, 2009 - The National Human Genome Research Institute (NHGRI) has awarded more than $113 million provided by the American Recovery and Reinvestment Act. The new awards, added to NHGRI's regularly appropriated $367 million budget, will more >>
- The Disease Machine - Can software synthesize what we know about human biology into one clear picture? Stephen Friend thinks so.
- Forbes - October 8, 2009 - During a six-year stint as head of cancer research at Merck, genetics entrepreneur Stephen Friend tried to inject a new kind of biology, synthesized from supercomputers and reams of biological data, into a staid drug maker as it more >>
- New Technology Provides Deeper Look into Building Blocks of Life
- San Jose Mercury News - September 25, 2009 - Slogging away in a Cornell University laboratory in teh late 1990s, graduate student Jonas Korlach conducted obscure experiments using a laser to glean data from a single molecule tucked in a chamber smaller more >>
- Stephen Turner on Forbes.com Video Network
- Stephen Turner being interviewed on Forbes.com more >>
- PacBio to Expand Apps for SMRT Platform; Initial Focus on Cancer, Infectious Disease Sequencing
- GenomeWeb - Sept 22, 2009 - The firm disclosed that it is collaborating with six early-access customers, including Monsanto and the Scripps Institute, on a variety of sequencing projects. It will soon finalize the list of institutions that will receive more >>
- PacBio Shows Proof of Principle for Methylation Sequencing, Direct RNA Sequencing
- Genome Web - Sept 17, 2009 - Pacific Biosciences has demonstrated that it can use its single-molecule real-time sequencing technology to identify methylated DNA bases, and to directly sequence RNA molecules. It has also applied strobe sequencing, more >>
- The New, Fast Gene Machine
- Forbes - September 16, 2009 - Steve Turner's DNA scanner is radically different from any other company's approach. more >>
- SMRT Software Braces for the Pacific Biosciences Tsunami
- Bio-ITWorld.com - September 18, 2009 - Earlier this year, Pacific Biosciences founder and CTO Stephen Turner ran an animation of a real-time single-molecule sequence trace as a crawl at the foot of his slides for the duration of his talk, demonstrating more >>
- Scientist at Work: Eric Schadt (NY Times Profile)
- New York Times - August 24, 2009 - For over a decade, Eric Schadt has been one of a handful of scientists blending mathematics, biology and supercomputers to pursue a new understanding of human biology, more >>
- Pocketing $68M, PacBio Remains on Track for Commerical Launch
- In Sequence - August 18, 2009 - Pacific Biosciences said last week that it has raised $68 million in financing from a combination of new and existing investors, brining its total VC financing to more than $260 million since it was founded in 2004 more >>
- Silicon Valley may be getting its mojo back
- San Jose Mercury News- August 12, 2009 - Is Silicon Valley gradually getting its mojo back? more >>
- Frontiers in Physics: Real Time DNA Sequencing
- Physics Today- August 3, 2009 - It took scientists more than twenty years after the first DNA sequencing technology was discovered to sequence the entire human genome; yet our own cells complete this task every time our bodies produces a daughter cell. more >>
- FierceBiotech's 2009 Fierce 15
- FierceBiotech- June 29, 2009 - After running in stealth mode for several years, Pacific Biosciences burst into the open with some of the most significant venture backing the industry has seen. more >>
- Pacific Biosciences Nets Eric Schadt as Chief Scientific Officer
- Bio-IT World- May 28, 2009 - Eric Schadt, the Merck biomathematician whose groundbreaking studies on disease pathways and genome data integration have drawn plaudits from the scientific community, is joining the next-generation sequencing company more >>
- PacBio Says 'Strobe Sequencing' Increases Effective Read Length of Single-Molecule Sequencer
- In Sequence- May 12, 2009 - Researchers at Pacific Biosciences have developed a new sequencing mode called "strobe sequencing" that enables them to increase the effective read length of their single-molecule real-time technology beyond 3 kilobases. more >>
- Getting personal
- The Economist- April 16, 2009 - The promise of cheap genome sequencing more >>
- Winning the Race
- Drug Discovery & Development - March 2, 2009 - Developers of next-generation and third-generation sequencing technologies compete for first place in the genomics marathon. more >>
- The DNA stakes
- San Francisco Chronicle - February 6, 2009 more >>
- Five Technologies Set to Change The Decade
- Forbes - January 7, 2009 - Amazing, new technologies will be woven into the fabric of our daily lives. more >>
- Interpreting the Genome
- MIT Technology Review - January/February 2009 - New technologies will soon make it possible to sequence thousands of human genomes. more >>
- PacBio Named Senior Party in USPTO Interference Involving VisiGen Patent
- In Sequence - March 31, 2009 - Pacific Biosciences said last week that it has been named the senior party in an ongoing US Patent and Trademark Office interference that involves a patent held by Life Technologies and a patent application filed by PacBio more >>
- PacBio Proof-of-Concept Paper Sheds Additional Light On SMRT Technology
- In Sequence - December 2, 2008 - An article published two weeks ago by Pacific Biosciences disclosed details of its sequencing technology and showed that the company can collect sequence data from single DNA polymerase enzymes. more >>
- Science Podcast
- Science- November 21, 2008- An interview with Jonas Korlach and Stephen Turner on real-time DNA sequencing from single polymerase molecues more >>
- Setting Expectations for '10 Launch, PacBio Reveals Some Specs for SMRT Sequencer
- In Sequence - October 14, 2008 - After undergoing a series of internal feasibility studies, Pacific Biosciences has determined a number of specifications for the first version of its single-molecules real-time sequencer, more >>
- Silicon Valley's hottest startup
- Fortune - October 3, 2008 - Pacific Biosciences' groundbreaking gene-sequencing technology could change healthcare more >>
- Mapping the human genome in 15 minutes
- Play Video
more >> - The Jiffy Lube of Genome Decoding
- DISCOVER - September 20, 2008 - A new company promises to map your DNA while-U-wait- for only a few hundred bucks. more >>
- DNA in Real Time
- Technology Review - September 16, 2008 - Pacific Biosciences aims to bring sequencing technology to the doctor's office. more >>
- Genomes 'R' Us
- Fortune - August 28, 2008 - Pacific Biosciences says it will soon be able to decipher the genetic code faster and cheaper than ever. more >>
- Company's lobster bash harkens back to a valley tradition
- San Jose Mercury News- August 21, 2008- Menlo Park company builds team spirit with annual event more >>
- Intel, Others Back New DNA Sequencer
- Wall Street Journal - July 14, 2008 - Investors are pumping $100 million into a start-up developing technology to propel DNA sequencing into mainstream medicine. more >>
- Hot Technology That Could Change Health Care
- Forbes - August 27, 2008 - Advances in health care run the gamut from mind-boggling medicines to simple Web solutions that, if adopted, could slice huge slabs of fat from a bloated system. more >>
- PacBio to Start Selling Next-Gen Sequencer To Early Users in 2010; Goal is 100 Gb/Hour
- In Sequence - February 12, 2008 - Providing a taste of what third-generation sequencing might look like, Pacific Biosciences last week outlined its single-molecule real-time, zero-mode waveguide DNA-sequencing technology ... more >>
- Pacific Biosciences Preparing the 15-Minute Genome by 2013
- Bio-IT World - February 12, 2008 - Midway through this year's "Advances in Genome Biology and Technology" conference, Pacific Biosciences sponsored a beachfront fireworks display to celebrate its emergence ...
more >> - California Company Claims Faster, Cheaper Gene Map
- Reuters - February 11, 2008 - Pacific Biosciences says its new gene-sequencing machines are far faster than existing equipment... more >>
- The Race to Read Genomes on a Shoestring, Relatively Speaking
- New York Times - February 9, 2008 - A person wanting to know his or her complete genetic blueprint can already have it done—for $350,000. But ...
more >>
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