Publications

The technology developed by Pacific Biosciences is described in the following publications:

A flexible and efficient template format for circular consensus sequencing and SNP detection
Kevin J. Travers, Chen-Shan chin, David R. Rank, John S. Eid and Stephen W Turner
Nucleic Acids Reserach, June 22, 2010, doi:10.1093/nar/gkq543 view publication >> 

Direct detection of DNA methylation during single-molecule, real-time sequencing
Benjamin A Flusberg, Dale R Webster, Jessica H Lee, Kevin J Travers, Eric C Olivares, Tyson A Clark, Jonas Korlach & Stephen W Turner
Nature Methods, 9 May 2010, doi:10.1038/nmeth.1459 view publication >>

Real-time tRNA transit on single translating ribosomes at codon resolution 
Sotaro Uemura, Colin Echeverria Aitken, Jonas Korlach, Benjamin A. Flusberg, Stephen W. Turner & Joseph D. Puglisi
Nature, Vol 464, 15 April 2010, doi:10.1038/nature08925 view publication >>

Real-Time DNA Sequencing from Single Polymerase Molecules
John Eid, Adrian Fehr, Jeremy Gray, Khai Lyong, John Lyle, Geoff Otto, Paul Peluso, David Rank, Primo Baybayan, Brad Bettman, Arakadiusz Bibillo, Keith Bjornson, Bidhan Chaudhuri, Frederick Christians, Ronald Cicero, Sonya Clark, Ravindra Dalal, Alex deWinter, John Dixon, Mathieu Foquet, Alfred Gaertner, Paul Hardenbol, Cheryl Heiner, Kevin Hester, David Holden, Gregory Kearns, Xiangxu Hong, Ronald Kuse, Yves Lacroix, Steven Lin, Paul Lunquist, Congcong Ma, Patrick Marks, Mark Maxham, Devon Murphy, Insil Park, Thang Pham, Michael Phillips, Joy Roy, Robert Sebra, Gene Shen, Jon Sorenson, Austin Tomaney, Kevin Travers, Mark Trulson, John Vieceli, Jeffrey Wegener, Dawn Wu, Alicia Yang, Denis Zaccarin, Peter Zhao, Frank Zhong, Jonas Korlach, Stephen Turner
Science, 02 January 2009/10.1126/science.1162986 view publication >>
view abstract

Long, Processive Enzymatic DNA Synthesis Using 100% Dye-Labeled Terminal Phosphate-Linked Nucleotides
Jonas Korlach, Arek Bibillo, Jeffrey Wegener, Paul Peluso, Thang T. Pham, Insil Park, Sonya Clark, Geoff A. Otto, Stephen W. Turner
Nucleosides, Nucleotides and Nucleic Acids, 27:1072:1083, 2008 view publication >>

Parallel confocal detection of single molecules in real time
Paul M. Lundquist, Cheng F. Zhong, Peiqian Zhao, Austin B. Tomaney, Paul S. Peluso, John Dixon, Brad Bettman, Yves Lacroix, Deborah P. Kwo, Etienne McCullough, Mark Maxham, Kevin Hester, Paul McNitt, Donald M. Grey, Carlos Henriquez, Mathieu Foquet, Stephen W. Turner, and Denis Zaccarin
Optics Letters, Vol. 33, Issue 9, pp. 1026-1028 view publication >>

Selective aluminum passivation for targeted immobilization of single DNA polymerase molecules in zero-mode waveguide nanostructures.
Korlach, J., Marks, P.J., Cicero, R.L., Gray, J.J., Murphy, D.L., Roitman, D.B., Pham, T.T., Otto, G.A., Foquet, M. & Turner, S.W
Proceedings of the National Academy of Sciences U.S.A. 105(4): 1176-1181. (2008)  view publication >>

Improved fabrication of zero-mode waveguides for single-molecule detection
Mathieu Foquet, Kevan T. Samiee, Xiangxu Kong, Bidhan P. Chaudhuri , Paul M. Lundquist, Stephen W. Turner, Jake Freudenthal, and Daniel B. Roitman
Journal of Applied Physics 103, 034301 (2008)  view publication >>

Zero-Mode Waveguides for Single-Molecule Analysis at High Concentrations
M. J. Levene, J. Korlach, S. W. Turner, M. Foquet, H. G. Craighead, W. W. Webb
SCIENCE 299:682-686, January 2003  view publication >>

To obtain a reprint of any of these publications, please send a request to mail to: info@pacificbiosciences.com